Clinical Research

A resource to get the latest clinical evidence, studies, models and frameworks to advance knowledge of how best to manage chronic health conditions.

Welldoc is committed to our scientific research, advancing digital health, transforming chronic care, and driving value across healthcare. Areas of focus include digital health engagement, advancing artificial intelligence, cardiometabolic condition outcomes, cost and value, and real-world integration into the health ecosystem.

Behavioral Factors, Empowerment Bolsters Self-Management

The increasing use of web-based or technology-enabled solutions for health management presents opportunities to improve patient self-management…
A Novel Approach to Continuous Glucose Monitoring
Health Plan Opportunities to Control Costs Related to Chronic Disease
Moving the Dial in Lowering and Controlling A1C
The Power of Integrated Peer Support and Digital Health
A Novel Approach to Continuous Glucose Monitoring
Health Plan Opportunities to Control Costs Related to Chronic Disease
Health Plan Opportunities to Control Costs Related to Chronic Disease
Moving the Dial in Lowering and Controlling A1C
The Power of Integrated Peer Support and Digital Health
The Power of Integrated Peer Support and Digital Health
Topics
Clinical Bibliography Theme
Type
Clinical Bibliography Type
Healthcare Models and FrameworksIntegration into Care
welldoc article
Article
Public-Private-Industry Learning Network: Digital Health Expands the Reach and the Role of the Diabetes Care and Education Specialist
Welldoc collaborated with the state of Montana and the Montana Diabetes Digital Health Learning Network (MDDHLN) to integrate digital health into their diabetes program. The intent was to scale services to better support Montana’s rural, frontier communities. This population typically has limited access to health resources and can benefit from innovative tools, like digital health platforms, to help better self-manage their diabetes. This article highlights the many learnings and best practices to efficiently and effectively implement novel cardiometabolic care models that integrate in-person, virtual and digital capabilities.

Malinda Peeples, MS, RN, CDCES, FADCES, Marci Butcher, RD, CDCES, FADCES, Jennifer Scarsi, RD, CDCES, Deb Bjorsness, MPH, BC-ADM, RD, CDCES, Melissa House, MBA, and Janice Macleod, MA, RD, CDCES, FADCES

Healthcare Analytics
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Poster
Use of a Diabetes Digital Health Solution Leads to Improvements in Cardiometabolic Outcomes
In this research, Welldoc demonstrates the potential for digital health solutions focused on diabetes to also address a broader set of cardiometabolic outcomes. A multi-condition approach could help health plans, health systems and care teams to better manage the complexities associated with diabetes, while also addressing other cardiometabolic health comorbid conditions. This work can also support better understanding of digital health engagement patterns and the impact to specific health outcomes, ultimately contributing to the development of predictive models and advanced artificial intelligence capabilities.

Abhimanyu Kumbara, MS, Anand Iyer, PhD, and Mansur Shomali, MD, CMO

Healthcare AnalyticsPatient Experience
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Poster
Using Early Engagement Data from a Digital Health Solution to Predict Future Glycemia Risk Index (GRI)
In this real-world analysis, Welldoc builds upon prior research to show early engagement data from a digital health solution can predict the future Glycemic Risk Indicator (GRI) metric* in people with type 1 or type 2 diabetes using a continuous glucose monitoring (CGM) device. This research could enable care teams to use early digital health engagement data to build more personalized and optimized care plans for individuals, and supports Welldoc's efforts in developing next-generation digital health solutions that can improve efficiencies and health outcomes.
*Reference: Klonoff DC, et al. A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings. J Diabetes Sci Technol. 2023 Sep;17(5):1226-1242. doi: 10.1177/19322968221085273. Epub 2022 Mar 29. PMID: 35348391.

Junjie Luo, MS, Abhimanyu Kumbara, MS, Anand Iyer, Ph, Mansur Shomali, MD, and Gordon Gao, PhD

Healthcare AnalyticsPatient ExperienceReal World Evidence
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Poster
The Use of a Digital Health Tool with AI-coaching for Patients Enrolled in a Virtual Diabetes Program is Associated with Improvements in Weight and Blood Pressure
In this real-world analysis, Welldoc shows how AI-driven digital coaching can provide personalized, whole-person support for individuals with multiple cardiometabolic conditions, like diabetes, hypertension, and obesity, and amplify the benefits of visits and communication with providers. These outcomes demonstrate how overall cardiovascular risk can be reduced in a high-risk population in a scalable manner, and support Welldoc’s efforts in developing next-generation digital health solutions that can improve health outcomes and increase access to care.

Mansur Shomali, MD, CM, Abhimanyu Kumbara, MS, MBA, and Anand Iyer, PhD, MBA

Healthcare AnalyticsPatient Experience
welldoc article
Article
Impact of a Combined Continuous Glucose Monitoring–Digital Health Solution on Glucose Metrics and Self-Management Behavior for Adults With Type 2 Diabetes: Real-World, Observational Study
In this journal article, Welldoc builds upon prior research focused on advancing chronic care through the use of digital health and real-time connected devices. This study examines the impact of combing real-time continuous glucose monitoring (RT-CGM) with an AI-driven digital health solution on helping individuals with type 2 diabetes to improve their glycemic metrics like time in range (TIR).

Abhimanyu B Kumbara; Anand K Iyer; Courtney R Green; Lauren H Jepson; Keri Leone; Jennifer E Layne; Mansur Shomali

Healthcare AnalyticsPatient Experience
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Poster
Examining The Ability of Different Machine Learning Approaches to Predict Health Outcomes with a Digital Health Platform
In this study, Welldoc builds upon our prior research on advancing digital health AI through machine learning (ML) and connection with real-time connected devices, such as continuous glucose monitoring (CGM). This study examines how CGM data combined with digital health My E-Diary for Activities and Lifestyle (MEDAL) data and behavior patterns can lead to better understanding of optimal digital health feature utilization and ML models, which can be used to predict future Time in Range (TIR). This research continues Welldoc's efforts in advancing our AI models and developing next generation digital health solutions geared towards personalized prevention and prediction.

Mansur Shomali, MD, CM, Abhimanyu Kumbara, MS, Junjie Luo, MS, Anand Iyer, PhD, Gordon Gao, PhD

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Taking Diabetes Self-Management to the Next Level